Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.

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Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade. (2016, unknown): “ABC transporters can be classified on the basis of the structure and sequence of the NBDs, also known as ABC domains [19,20].”
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease (2015, unknown): “Phase III of drug metabolism involves the active transport of conjugated metabolites across the cell membrane by transport proteins, such as the ATP-binding cassette family of transporters, including multidrug resistance [56] and multidrug-resistance-associated protein (MRP) [57], where they can be ”
Glutathione dysregulation and the etiology and progression of human diseases (2009, background): “Elevated expression of MRP1 has been observed in a variety of hematological and solid tumors, and increased expression levels of other MRP transporters are found in a few cancerous tissues (Leslie et al., 2005; Deeley et al., 2006).”