How stress influences the immune response.

By D. Padgett, R. Glaser. Trends in immunology, 2003

1,030 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Endocrinology, Diabetes and Metabolism, Immunology

View Paper: https://www.semanticscholar.org/paper/88a62743af3b95c0e2c8ea74868587588bd2e4c0

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In Behavioral Neuroscience

1. Paul R. Martin
2. F. Bonier
3. John M. McNamara
4. K. Buchanan
5. J. Wingfield
6. Bruce S. McEwen
7. Carol Worthman

In Endocrinology, Diabetes and Metabolism

1. J. Wingfield

Citations in the corpus

• Impact of heat stress and nutritional interventions on poultry production (2018, background): “For instance, glucocorticoid receptor binds cortisol which interferes with the function of NF-kB, regulating the activity of cytokineproducing immune cells (Padgett and Glaser, 2003).”
• Stress, resource allocation, and mortality (2005, background): “Under chronic stress there is also a downregulation of the immune system, thought to occur in part through the action of the neuroendocrine system (Brown, 1994; Padgett and Glaser, 2003).”
• High intelligence: A risk factor for psychological and physiological overexcitabilities (2018, background): “…extremely likely to possess a high cognitive ability, produced weaker immune responses to a vaccine then we might conclude these same individuals who are chronically stressed would be slower to develop a proper immune response to various other insults and pathogens as well (Padgett & Glaser, 2003).”
• Urbanization and the ecology of wildlife diseases (2006, background): “Changes in stress and pollution along the urban‐rural gradient could also affect host susceptibility to infectious diseases (Table 1). Among vertebrate animals, chronic stress can lower resistance to infection and intensify the harmful effects of pathogens through effects on the host immune system [”
• Sex-specific consequences of life in the city (2007, background): “Elevated cort can lead to suppression of the reproductive and immune systems (Sapolsky et al. 2000; Padgett and Glaser 2003; Retana-Marquez et al. 2003) and may result in reallocation of resources away from reproduction.”
• Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions (2018, background): “Agency focus on mitigating stress and optimizing crew health likely benefits the immune function of the crew, based on the established terrestrial literature which demonstrates that minimizing stress, sleep loss, and circadian misalignment is related to improved immune function (202, 203).”
• Impact of Heat Stress on Poultry Production (2013, background): “This topic has been the subject of several extensive reviews [34–37].”
• Roles of Raptors in a Changing World: From Flagships to Providers of Key Ecosystem Services (2016, background): “foraging and resting sites) has been linked to chronic stress, which can lower resistance to infection and intensify the harmful effects of pathogens through effects on the host immune system (Sol et al., 1998; Padgett and Glaser, 2003).”
• Urbanization and Disease Emergence: Dynamics at the Wildlife–Livestock–Human Interface (2017, background): “Environmental stressors such as heavy metal and pesticide pollutants, characteristic of certain urban environments, can further compound these outcomes through their effects on immunological function [83].”
• Maternal yolk testosterone does not modulate parasite susceptibility or immune function in great tit nestlings (2005, positive): “Grossman 1985; Alexander & Stimson 1988), enhance parasite susceptibility (Zuk & McKean 1996; Schalk & Forbes 1997; Poiani, Goldsmith & Evans 2000) or indirectly exert an immunosuppressive effect via an increase in circulating glucocorticoids (Gross, Siegal & DuBose 1980; Ketterson et al . 1991; De ”
• Exposure to a Social Stressor Alters the Structure of the Intestinal Microbiota: Implications for Stressor-Induced Immunomodulation (2010, background): “The mechanisms by which the stress response can suppress immune functioning are well understood, and are known to involve glucocorticoid mediated suppression of transcription factors, such as NF-jB (Padgett and Glaser, 2003).”
• The Vaginal Microenvironment: The Physiologic Role of Lactobacilli (2018, background): “Immune response may be impaired by stress-related activation of the hypothalamic-pituitary adrenal (HPA) axis and secretion of corticotropin-releasing hormone (CRH) from the hypothalamus, which activates the release of cortisol from the adrenal cortex and noradrenaline from sympathetic nerve termina”