Molecular psychology: roles for the ERK MAP kinase cascade in memory.

By J. Adams, J. Sweatt. Annual Review of Pharmacology and Toxicology, 2002

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Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development (2007, background): “The MAPK-signalling pathway is considered to be a crucial player in synaptic plasticity and many cognitive function”
Long-term potentiation and memory. (2004, background): “Consistently, PKA activation by forskolin was shown to strongly activate ERK2 in hippocampal area CA1 while its effect on ERK1 was slight (9).”
Insulin Action in Brain Regulates Systemic Metabolism and Brain Function (2014, background): “This pathway also contributes to the normal function and survival of neuronal cells (24).”
Active Protection: Learning-Activated Raf/MAPK Activity Protects Labile Memory from Rac1-Independent Forgetting. (2018, positive): “Learning Activates Raf/MAPK Activity in a Brain Region Where Labile Memory Is Formed Learning-activated Raf/MEK/MAPK pathway plays an essential role in the consolidation of long-term memory (Adams and Sweatt, 2002; Sweatt, 2001; Thomas and Huganir, 2004), including that in Drosophila (Li et al.”
The molecular logic of endocannabinoid signalling (2003, background): “This process, which is necessary to produce lasting changes in synaptic strength, depends on the recruitment of complex networks of intracellular protein kinase”