Guidance document on delivery, treatment planning, and clinical implementation of IMRT: report of the IMRT Subcommittee of the AAPM Radiation Therapy Committee.
By G. Ezzell, J. Galvin, D. Low, J. Palta, I. Rosen, M. Sharpe, P. Xia, Ying Xiao, Lei Xing, Cedric X. Yu. Medical Physics (Lancaster), 2003
910 citations recorded by the source corpus.
Intensity-modulated radiation therapy (IMRT) represents one of the most significant technical advances in radiation therapy since the advent of the medical linear accelerator. It allows the clinical implementation of highly conformal nonconvex dose distributions. This complex but promising treatment modality is rapidly proliferating in both academic and community practice settings. However, these advances do not come without a risk. IMRT is not just an add-on to the current radiation therapy process; it represents a new paradigm that requires the knowledge of multimodality imaging, setup uncertainties and internal organ motion, tumor control probabilities, normal tissue complication probabilities, three-dimensional (3-D) dose calculation and optimization, and dynamic beam delivery of nonuniform beam intensities. Therefore, the purpose of this report is to guide and assist the clinical medical physicist in developing and implementing a viable and safe IMRT program. The scope of the IMRT program is quite broad, encompassing multileaf-collimator-based IMRT delivery systems, goal-based inverse treatment planning, and clinical implementation of IMRT with patient-specific quality assurance. This report, while not prescribing specific procedures, provides the framework and guidance to allow clinical radiation oncology physicists to make judicious decisions in implementing a safe and efficient IMRT program in their clinics.
Subfields: Pulmonary and Respiratory Medicine, Radiation, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/879051864d1904edbd94481f610b9395a04a9a20
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Citations in the corpus
- Validation of an accelerated ‘demons’ algorithm for deformable image registration in radiation therapy (2005, background): “Recent advances in three-dimensional conformal radiotherapy (3DCRT) and intensitymodulated radiation therapy (IMRT) allow more precise tumour targeting and preservation of normal tissues (Ezzell et al 2003, Mackie et al 2003).”