Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome
By S. Wong, K. M. Chow, T. Leung, Wai-fu Ng, T. Ng, C. Shek, P. Ng, P. W. Y. Lam, L. Ho, W. To and 3 more. American Journal of Obstetrics and Gynecology, 2004
958 citations recorded by the source corpus.
Objective This study was undertaken to evaluate the pregnancy and perinatal outcomes of pregnant women with severe acute respiratory syndrome (SARS). Study design All pregnant women (12) who presented with SARS in Hong Kong between February 1 and July 31, 2003, were included. The pregnancy and perinatal outcomes were collected. Evidence of perinatal transmission of virus was assessed with the SARS-associated coronavirus reverse-transcriptase polymerase chain reaction on cord blood, placenta tissue, and subsequent follow-up of the neonate on serology. Results Three deaths occurred among the 12 patients, giving a case fatality rate of 25%. Four of the 7 patients (57%) who presented in the first trimester had spontaneous miscarriage. Four of the 5 patients who presented after 24 weeks were delivered preterm. Two mothers recovered without delivery, but their ongoing pregnancies were complicated by intrauterine growth restriction. No newborn infant had clinical SARS and all investigations were negative for SARS. Conclusion SARS during pregnancy is associated with high incidences of spontaneous miscarriage, preterm delivery, and intrauterine growth restriction. There is no evidence of perinatal SARS infection among infants born to these mothers.
Subfields: Obstetrics and Gynecology
View Paper: https://www.semanticscholar.org/paper/874f601b503c97de92aa0390ce40157d4cb94a84
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Citations in the corpus
- Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records (2020, neutral): “10,16 However, our observation of no fetal infection caused by intrauterine vertical transmission could be affected by our small sample size and the stage of pregnancy at the onset of COVID-19 infection.”
- Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study (2020, background): “18, 20 One neonate in our study was infected with COVID-19 36 h after birth.”
- Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know (2020, background): “Pregnancy outcomes varied by trimester of presentation.(10) Among the 7 women who became ill in the first trimester, 4 had a spontaneous abortion, 2 had pregnancy terminations for social reasons after recovery from SARS, and 1 delivered a full-term healthy infant.”
- An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. (2020, background): “In addition, 4 of 5 pregnancies resulted in preterm birth: 1 spontaneous and 3 induction deliveries that were performed for maternal conditions.(26) Vertical transmission of the SARS-CoV virus did not occur in any of the infants; however, the clinical outcomes of pregnant women with SARS were worse ”
- Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis (2020, methodology): “Ribavirin was used by Wong et al.(30); b Maternal (not fetal) indications; * Raw proportions; ** A pooled proportion is”
- Coronavirus disease 2019 (COVID-19) pandemic and pregnancy (2020, neutral): “Although most human coronavirus infections are mild, the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) epidemics of the past two decades have been especially grave, with approximately onethird of infected pregnant women dying fro”
- Potential Maternal and Infant Outcomes from Coronavirus 2019-nCoV (SARS-CoV-2) Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections (2020, background): “[29] evaluated the obstetrical outcomes from a cohort of pregnant women who developed SARS in Hong Kong during the period of 1 February to 31 July 2003.”
- Coronavirus Infections in Children Including COVID-19 (2020, background): “However, SARS-CoV infections during pregnancy have been associated with possible miscarriage, intrauterine growth retardation and preterm delivery.(137,138)”