Effect of blood transfusion on long-term survival after cardiac operation.

By M. Engoren, R. Habib, A. Zacharias, T. Schwann, C. Riordan, S. Durham. Annals of Thoracic Surgery, 2002

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Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting* (2006, background): “Previous investigations have been limited by examining PRBC transfusion as a binary variable (1, 12), thereby limiting examination of a dose-dependent effect, have not included both intraoperative and postoperative PRBC transfusions (1), or have not included the influence of blood components such as”
Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial. (2010, background): “However, transfusions have been associated with high rates of morbidity and mortality in critically ill patients,(6) and some recent studieshaveshownworseoutcomes, including increased occurrence of renal failure and infection, as well as respiratory, cardiac, and neurologic complications, in transfu”
2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines. (2011, neutral): “and long-term outcomes [7, 8].”