Neurons in the Frontal Lobe Encode the Value of Multiple Decision Variables

By SW Kennerley, Aspandiar F. Dahmubed, Antonio H. Lara, Jonathan D. Wallis. Journal of Cognitive Neuroscience, 2009

440 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, General Decision Sciences

View Paper: https://www.semanticscholar.org/paper/868751cda9531f176d36d3bce1bcf8973f547094

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Citations in the corpus

Surprise signals in anterior cingulate cortex: Neuronal encoding of unsigned reward prediction errors driving adjustment in behavior (2011, background): “The results we present here are consistent with a growing body of literature linking ACC in general and dACC in particular with associating actions and their reward outcomes (Procyk et al., 2000; Shidara and Richmond, 2002; Williams et al., 2004; Amiez et al., 2005; Sallet et al., 2007; Seo and Lee,”
Neural computations associated with goal-directed choice. (2010, methodology): “These findings suggest a dissociation between the OFC and areas of the ACC and SMA in goal-directed choice, with the former being specialized in the encoding of stimulus values, and the latter in the encoding of action values [19,32].”
Separate Valuation Subsystems for Delay and Effort Decision Costs (2010, background): “…the integrated value of a course of action, encoding a combination of several decision variables, such as potential reward amount and effort cost (Kennerley et al., 2009) and with the fact that ACC neurons encode a monkey’s progression through the series of work steps toward reward—although in…”
Social and monetary reward learning engage overlapping neural substrates. (2012, background): “, 2010) and non-human primate electrophysiological studies (Wallis and Miller, 2003; Padoa-Schioppa and Assad, 2006, 2008; Kennerley et al., 2009; Kennerley and Wallis, 2009; Padoa-Schioppa, 2009) during choices involving non-social rewards, as well as during social decisions such as donations to ch”
An opportunity cost model of subjective effort and task performance (2013, positive): “…the anterior cingulate also shift animals’ preferences away from high effort–high reward options (Rudebeck et al. 2006; Walton et al. 2003), and the costs of physical effort are robustly encoded in this region (Croxson et al. 2009; Kennerley et al. 2009; Kurniawan et al. 2010; Prevost et al. 2010).”
Informatic parcellation of the network involved in the computation of subjective value. (2014, background): “This area has had several wide classes of computations attributed to it, including decision and strategic control (Venkatraman et al., 2009), environment volatility (Behrens et al., 2007) and multiplexing of decision parameters (Kennerley et al., 2009; Hayden and Platt, 2010; Hare et al., 2011b).”
Reconsidering Anhedonia in Depression: Lessons from Translational Neuroscience (2010, background): “More unique to the ACC is the specialized role of making reward choices, particularly during more complex decisions that require the integration of both cost and benefits (Kennerley et al., 2009; Kennerley et al., 2006; Rushworth and Behrens, 2008; Walton et al., 2006).”
The expected value of control: An integrative theory of anterior cingulate cortex function (2013, positive): “Neurons in dACC have been found to track the effort demands of a prospective action, whether this involves lever presses (Kennerley et al., 2011; Kennerley et al., 2009) or physical obstacles that need to be overcome along a path (Cowen et al.”
The valuation system: A coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value (2013, positive): “At the single neuron level, however, there seem to be roughly equal numbers of neurons that increase or decrease firing as SV changes (Kennerley et al., 2009).”
The Computation of Stimulus Values in Simple Choice (2014, background): “For example, neurons in dmPFC have been shown to reflect several different decision variables (Kennerley et al., 2009, 2011), making this region ideally qualified to compare the SVs and ACs of different options and select the best course of action.”
NEUROBIOLOGY OF ECONOMIC CHOICE: A GOOD-BASED MODEL (2011, background): “In another study, Kennerley et al. (2009) found a sizable population of OFC neurons modulated by three variables: the juice quantity, the action cost, and the probability of receiving the juice at the end of the trial.”
Emotion and the Prefrontal Cortex: An Integrative Review (2017, background): “Notably, the aMCC is sensitive to the number and difficulty of actions that must be performed to obtain a desired outcome (Croxson et al., 2009; Kennerley et al., 2009; Kurniawan, Guitart-Masip, Dayan, & Dolan, 2013; Shidara & Richmond, 2002).”