High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

By I. Yuhanna, Yan Zhu, B. Cox, L. Hahner, S. Osborne-Lawrence, P. Lu, Y. Marcel, R. G. Anderson, M. Mendelsohn, Helen H. Hobbs and 1 more. Nature Medicine, 2001

765 citations recorded by the source corpus.

Subfields: Cell Biology, Immunology, Surgery

View Paper: https://www.semanticscholar.org/paper/8623cf765ef023ccec1d95e0a1f29b19f864e793

How researchers see this paper

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In Cell Biology

1. J. Chun

In Immunology

1. J. Chapman
2. A. Kontush

In Surgery

1. A. Kontush
2. J. Chapman
3. G. Assmann

Citations in the corpus

• Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis (2006, background): “Such activation of NO production involves HDL binding to SR-BI with a subsequent increase in intracellular ceramide levels (Yuhanna et al., 2001; Li et al., 2002).”
• HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3. (2004, background): “Therefore, the interaction of HDL with SR-BI could provide the necessary spatial proximity for SPC, S1P, and LSF to effectively stimulate S1P3.”
• Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. (2005, neutral): “84 FH heart disease/HTN/ lipid abnormality 73 (36) 68 (38) 0.”