High-frequency neural activity and human cognition: past, present and possible future of intracranial EEG research

By Jean-Philippe Lachaux, Nikolai Axmacher, Florian Mormann, Eric Halgren, Nathan E. Crone. 2012

Subfields: Cognitive Neuroscience, Neuroscience

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In Cognitive Neuroscience

Citations in the corpus

Human auditory cortex preferentially tracks speech over music without explicit attention (2026, unknown): “…with high spatial and temporal resolution (Berezutskaya et al., 2017; Chang, 2015; Flinker et al., 2011; Hamilton et al., 2021; Howard et al., 2000; Lachaux et al., 2012; Mercier et al., 2022; Micheli et al., 2020; Ozker et al., 2017), and provides basic science insights into local circuit…”
Temporal order of activations and interactions during arithmetic calculations measured by intracranial electrophysiological recordings in the human brain (2026, unknown): “While the exact mechanisms generating HGB remain a matter of debate, their most notable property has become well-established: they provide high temporal-resolution evidence for the participation of local neural populations during the task-at-hand 39,40 .”
Neural representations of visual memory in inferotemporal cortex reveal a generalizable framework for translating between spikes and field potentials (2026, unknown): “The ability to invasively record from the human brain has ushered in an exciting new era of neuroscience research [16, 18, 56–61].”
Multi-task Intracranial EEG recordings reveal a Comprehensive Role of the Human Dorsal Anterior Insula in High-Level Cognition (2025, unknown): “…using intracerebral electroencephalography (iEEG) in neurological patients, offer a unique opportunity to bypass the technical limitations of fMRI ( Lachaux et al. ( 2012 ); ( Mercier and others ( 2022 )), and several iEEG studies of the insula have already yielded valuable insights into its…”
Neural correlates of perceptual consciousness from within: A narrative review of human intracranial research (2025, unknown): “…limit the analysis of high-frequency components ( Cohen, 2014 ; Pfurtscheller and Cooper, 1975 ), intracranial signals capture brain oscillations in the high gamma range that have been associated with local neuronal firings ( Lachaux et al., 2012 ; Nir et al., 2007 ; Ray and Maunsell, 2011 ).”
Processing of auditory feedback in perisylvian and insular cortex (2024, methodology): “For all analyses, we extracted the high gamma analytic amplitude of the local field potentials (Lachaux et al., 2012), which has been shown to correlate with single-and multi-unit neuronal firing (Ray & Maunsell, 2011) and tracks both acoustic and phonological characteristics of speech (Mesgarani…”
Neural interactions in the human frontal cortex dissociate reward and punishment learning (2024, background): “As a reminder, mutual information is defined as: In this equation, the variables X and Y represent the across-trials gamma-band power and the PE variables, respectively.”
Simultaneous invasive and non-invasive recordings in humans: A novel Rosetta stone for deciphering brain activity (2024, unknown): “On the other hand, iEEG has emerged as the gold standard for studying brain functions due to its exceptional spatiotemporal resolution (Lachaux et al., 2012; Mercier et al., 2022), which is essential for modeling processes operating at subsecond scales.”
An intracranial dissection of human escape circuits (2024, unknown): “One possible explanation is that the reduction of HGA in the frontal lobe may recruit the shortcut of the reactive system, which facilitates more effective responses to emergencies 39 .”
Neuronal Avalanches in Naturalistic Speech and Music Listening (2023, methodology): “In this work, we focused on (the binarization of) HFa signals, which are generally used to provide insights into the neural bases of cognition (52).”