A Fast, Reciprocal Pathway between the Lateral Geniculate Nucleus and Visual Cortex in the Macaque Monkey

By F. Briggs, W. Martin Usrey. 2007

97 citations recorded by the source corpus.

Neurons in the lateral geniculate nucleus (LGN) not only provide feedforward input to primary visual cortex (V1), but also receive robust feedback from the cortex. Accordingly, visual processing in the LGN is continuously influenced by previous patterns of activity. This study examines the temporal properties of feedforward and feedback pathways between the LGN and V1 in the macaque monkey to provide a lower bound on how quickly the cortex can influence the LGN. In so doing, we identified a subclass of corticogeniculate neurons that receives direct, suprathreshold input from the LGN that is similar in latency to that directed to other recipient neurons (4.2 ± 0.4 vs 4.0 ± 0.2 ms). These neurons also provide feedback to the LGN that is significantly shorter in latency than that supplied by corticogeniculate neurons lacking LGN input (5.1 ± 1.3 vs 11.1 ± 2.3 ms, respectively). Across our sample of corticogeniculate neurons, the shortest combined visual response latency and feedback latency was 37 ms (mean, 52.5 ± 3.8 ms), indicating that visual signals can rapidly travel from the periphery to the cortex and back to the LGN.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. S. Shipp
2. Dana H. Ballard
3. Janneke F. M. Jehee

In Cognitive Neuroscience

1. S. Shipp
2. Dana H. Ballard
3. Janneke F. M. Jehee
4. Jacqueline Gottlieb
5. Keith Rayner

Citations in the corpus

• Neural Elements for Predictive Coding (2016, background): “…by corticogeniculate neurons should not be thought surprising, as corticogeniculate neurons themselves are known to receive direct contacts from LGN axons, either through branching of the apical dendrite in layer 4C or through geniculate axon collaterals in layer 6 (Briggs and Usrey, 2007, 2009).”
• Predictive Feedback Can Account for Biphasic Responses in the Lateral Geniculate Nucleus (2009, result): “Although this estimate is likely at the longer end of the range [76], the model does not critically depend on the value of this parameter and similar results would have been obtained using shorter time Figure 6.”