Tumor necrosis factor receptor-associated factors (TRAFs)

By J. Bradley, J. Pober. Oncogene, 2001

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The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. (2011, background): “Alternatively, the MAP3Ks and MAP4Ks of the cascade can be directly activated also by stimulated interactionwith adaptor proteins such as TRAF [30].”
The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma. (2003, unknown): “Median age, y (range) 32 (14-59) 64 (20-92)”
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB (2003, methodology): “This was immunoprecipated with either non-immune serum (n.i.) or Flag antibody from both untreated cells (basal) or cells treated for 20 min. with TNF-a(20 0 ) and lysates were incubated with GST-IkBa (1-72) in the presence of 32P-gATP (upper panel).”