Green synthesis, characterization, antibacterial and biofilm inhibitory activity of silver nanoparticles compared to commercial silver nanoparticles

By H. Barabadi, F. Mojab, H. Vahidi, Boshra Marashi, Niloufar Talank, Omid Hosseini, M. Saravanan. Inorganic Chemistry Communications, 2021

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Abstract This study was aimed to fabricate Zataria multiflora-derived silver nanoparticles (AgNPs) and evaluate the antibacterial activity and biofilm inhibitory activity of plant-mediated fabricated AgNPs (P-AgNPs) compared to commercial AgNPs (C-AgNPs) against Staphylococcus aureus ATCC 25923. The P-AgNPs were characterized by using UV-vis spectroscopy, Transmission electron microscopy (TEM), Scanning Electron Microscopy (SEM), Atomic Force Microscope (AFM), Energy Dispersive X-ray spectroscopy (EDX), Dynamic Light Scattering (DLS), and Fourier Transform Infrared (FT-IR) spectrum. The P-AgNPs were formed fairly uniform in size with a spherical morphology and an average hydrodynamic diameter of 25.5 nm at pH value of 9. Besides, the EDX analysis confirmed the presence of silver ions in the fabricated P-AgNPs. The FT-IR analysis also confirmed the presence of different functional groups on the surface of P-AgNPs. The P-AgNPs and C-AgNPs represented significant antibacterial activity with minimum inhibitory concentration (MIC) of 4 and 8 µg/mL against S. aureus, respectively. Both P-AgNPs and C-AgNPs at the concentrations of 0.5, 1, 2, and 4*MIC caused strong biofilm, weak biofilm, weak biofilm and no biofilm, respectively. Notably, at the concentrations of ≥8, both types of AgNPs exhibited significant biofilm inhibitory activity, whereas at the lower concentrations, the P-AgNPs showed greater biofilm inhibition formed by S. aureus.

Subfields: Electronic, Optical and Magnetic Materials, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/85749364c3272dd6cb08603ddab34ebf67545570