The Transporter Classification Database
By Milton H. Saier Jr., Vamsee S. Reddy, Dorjee G. Tamang, Åke Västermark. Nucleic Acids Res., 2013
481 citations recorded by the source corpus.
The Transporter Classification Database (TCDB; http://www.tcdb.org) serves as a common reference point for transport protein research. The database contains more than 10 000 non-redundant proteins that represent all currently recognized families of transmembrane molecular transport systems. Proteins in TCDB are organized in a five level hierarchical system, where the first two levels are the class and subclass, the second two are the family and subfamily, and the last one is the transport system. Superfamilies that contain multiple families are included as hyperlinks to the five tier TC hierarchy. TCDB includes proteins from all types of living organisms and is the only transporter classification system that is both universal and recognized by the International Union of Biochemistry and Molecular Biology. It has been expanded by manual curation, contains extensive text descriptions providing structural, functional, mechanistic and evolutionary information, is supported by unique software and is interconnected to many other relevant databases. TCDB is of increasing usefulness to the international scientific community and can serve as a model for the expansion of database technologies. This manuscript describes an update of the database descriptions previously featured in NAR database issues.
Subfields: Biochemistry, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/85331cdfdae93103b0c86bcb12bb1b47158ced08
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In Biochemistry
In Molecular Biology
- Vamsee S. Reddy
- Gabriel Moreno-Hagelsieb
- Chun Li
- Muhammad Saad Ahmed, Ph.D.
- Brian V. Tsu
- Milton H. Saier Jr.
- Nicole J. Yang
- Marlon J. Hinner
In Oncology
- Vamsee S. Reddy
- Gabriel Moreno-Hagelsieb
- Chun Li
- Muhammad Saad Ahmed, Ph.D.
- Brian V. Tsu
- Nicole J. Yang
- Marlon J. Hinner
Citations in the corpus
- The Transporter Classification Database (TCDB): recent advances (2015, methodology): “Earlier versions of the TC database (TCDB) have been described in previous publications in Nucleic Acids Research (7,9,10).”
- Getting Across the Cell Membrane: An Overview for Small Molecules, Peptides, and Proteins (2015, background): “org) [48] and the Solute Carrier (SLC) Tables (www.”
- Structure and mechanism of ABC transporters (2015, unknown): “org] for details) [3].”