Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis.

By J. Witlox, L. Eurelings, J. D. de Jonghe, K. Kalisvaart, P. Eikelenboom, W. V. van Gool. Journal of the American Medical Association (JAMA), 2010

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Effectiveness of multi-component non-pharmacologic delirium interventions: A Meta-analysis (2015, neutral): “The remaining articles were evaluated and excluded if they failed the following second-level inclusion criteria: (1) they studied multicomponent nonpharmacological delirium interventions, (2) they assessed delirium incidence and not prevalence, and (3) they used a validated delirium instrument for a”
One-year health care costs associated with delirium in the elderly population. (2008, result): “These findings, demonstrating a link between delirium and mortality, are consistent with results observed in other populations of individuals affected by delirium in the hospital setting.(44,45) Consequently, this systematic review underscores opportunities to improve the quality and organization of”
Microglia and neurodegeneration: The role of systemic inflammation (2013, background): “…the consistent clinical observation that patients who experience systemic infections or inflammation arising from surgery or injury do not fare well: they frequently suffer episodes of delirium, and these episodes typically lead to accelerated cognitive and functional decline (Witlox et al., 2010).”