HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers.

By Marc L. Mendillo, S. Santagata, M. Koeva, George W. Bell, R. Hu, R. Tamimi, E. Fraenkel, T. Ince, L. Whitesell, Susan Lindquist. Cell, 2012

696 citations recorded by the source corpus.

Subfields: Molecular Biology, Physical and Theoretical Chemistry

View Paper: https://www.semanticscholar.org/paper/84b948dd82937b74410ec8cf9098b248d17e4483

Citations in the corpus

• Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape (2016, neutral): “While plant HSFs have not been implicated in mitosis, a recent study of the human HSF1 indicates that this family may directly regulate cell division in proliferating cancer cells (Mendillo et al., 2012).”
• Mutant p53 as a guardian of the cancer cell (2018, neutral): “invasion, and inhibition of apoptosis [68].”