Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer.

By R. Flanigan, S. Salmon, B. Blumenstein, S. Bearman, V. Roy, P. Mcgrath, J. Caton, N. Munshi, E. Crawford. New England Journal of Medicine, 2001

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Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma (2003, background): “better the survival after immunotherapy.(5,6) Patients who are at high risk for developing subsequent metastases after surgery may harbor subclinical metastases at the time of presentation and may derive the greatest benefit from adjuvant therapy.”
MicroRNA signature predicts survival and relapse in lung cancer. (2008, methodology): “To seek statistical evidence for supporting the one-sided hypothesis that the high risk score of microRNA signature can predict poor survival in NSCLC patients, the combined samples of testing set and independent cohort were analyzed with the one-sided log-rank test (Flanigan et al., 2001; Seymour e”