Iron oxide MR contrast agents for molecular and cellular imaging

By J. Bulte, D. Kraitchman. NMR in Biomedicine, 2004

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Tuning the Magnetic Properties of Nanoparticles (2013, background): “The past decade has seen numerous studies evaluating the effect of the core as well as the coating on the relaxation of the surrounding protons for their use as MRI contrast agents [120,121].”
Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles (2007, background): “Recently, superparamagnetic iron oxide nanoparticles (SPION) are also attractive, which were introduced as contrast agents shortly after the use of gadolinium chelates, and currently appear to be the preferred material.(86) The interest on SPION labeling is mainly because of the many excellent prope”
Magnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications (2013, background): “By adjusting the core size, coating thickness, surface chemistry, and targeting ligands, the nanoprobes can be tailored to target specific organs, cells or even molecular markers of different diseases in vivo [90,102].”