Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

By A. Taly, P. Corringer, D. Guédin, P. Lestage, Jean-Pierre Changeux. Nature reviews. Drug discovery, 2009

720 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/84495f4fc21bb969445270b5da699769f7de67a5

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In Molecular Biology

1. P. Gentry
2. Thomas P Mathews
3. Roderick E. Hubbard
4. Cody J. Wenthur
5. Craig Lindsley

Citations in the corpus

• Structure-based drug discovery and protein targets in the CNS. (2011, background): “how ligand function (Taly et al., 2009) 2bg9 Category 3”
• Drugs for allosteric sites on receptors. (2014, background): “Extensive metabolic profiling led to the discovery that M1 (22, Figure 6b), an oxidative metabolite of VU0403602 (21), was a potent allosteric mGlu5 agonist that elicited the epileptiform activity—not the parent drug.”