An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7.
By Sejeong Shin, B. Sung, Yong-Soon Cho, Hyun-Jin Kim, N. Ha, Jong-Ik Hwang, C. Chung, Y. Jung, B. Oh. Biochemistry, 2001
712 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/8437aae61468c5510eb799920f1ca08c0ba69001
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In Oncology
Citations in the corpus
- Survivin, versatile modulation of cell division and apoptosis in cancer (2003, background): “However, with the exception of two published studies (Conway et al., 2000; Shin et al., 2001), this did not seem to translate in meaningful inhibition of caspase activity, in vitro (Banks et al., 2000; Kasof and Gomes, 2000; Verdecia et al., 2000).”
- Validating survivin as a cancer therapeutic target (2003, background): “However, with the exception of two published studie”