Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene

By M. Lim, Zuoxin Wang, D. Olazábal, Xianghui Ren, E. Terwilliger, L. Young. Nature, 2004

609 citations recorded by the source corpus.

Subfields: Experimental and Cognitive Psychology, Social Psychology, Sociology and Political Science

View Paper: https://www.semanticscholar.org/paper/842a1b62b0cbced738abb2d7ded2e40bfbb3cdb2

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Citations in the corpus

A neurobehavioral model of affiliative bonding: implications for conceptualizing a human trait of affiliation. (2005, background): “BEHAVIORAL AND BRAIN SCIENCES (2005) 28:3 329 Basolateral Amygdala”
The Challenge of Translation in Social Neuroscience: A Review of Oxytocin, Vasopressin, and Affiliative Behavior (2010, background): “Ne In fact, expressing the V1a receptor in the meadow vole ventral pallidum is sufficient to induce pair-bond-like behavior after mating in this nonmonogamous vole (Lim et al., 2004).”
Do hormonal control systems produce evolutionary inertia? (2008, background): “B (2008) regulatory elements (Britten & Davidson 1971; Lim et al. 2004).”
Neuroenhancement of Love and Marriage: The Chemicals Between Us (2008, background): “In one striking experiment, researchers used gene therapy to introduce a gene (the vasopressin receptor gene) from the monogamous male prairie vole, a rodent which forms life-long bonds with one mate, into the brain of the closely related but polygamous meadow vole [46].”
Reward, motivation, and emotion systems associated with early-stage intense romantic love. (2005, background): “The ventral pallidum has been implicated in attachment in prairie voles (Lim et al. 2004; Lim and Young 2004).”
The social role of touch in humans and primates: behavioural function and neurobiological mechanisms. (2010, background): “Experimentally manipulating the density of vasopressin receptors in the ventral pallidum using viral vectors, for example, directly affects the strength of partner preference in the absence of mating in male voles (Pitkow et al., 2001; Lim et al., 2004).”
Neuropeptidergic regulation of affiliative behavior and social bonding in animals. (2006, background): “Genetic sequencing of the prairie and montane vole avpr1a gene revealed much larger differences in the avpr1a promoter sequence, concentrated in a large stretch of tandem repeats known as microsatellite DNA (reviewed in Hammock and Young, 2002; Lim et al., 2004a) (Fig.”
The Biology of Paternal Care in Human and Nonhuman Primates (2009, background): “…of the neural circuitry underlie pair-bonding and paternal behavior in voles: a cognitive component required for individual recognition and an emotional component that provides the reward for engaging with particular other individuals (Lim et al. 2004b; Liu et al. 2001; Young et al. 2001, 2005).”
Dendritic peptide release and peptide-dependent behaviours (2006, background): “Moreover, experiments involving gene manipulation, either through transgenic mutation”
Domestication—From behaviour to genes and back again § (2006, background): “For example, in voles, experimentally changing the expression level of one single gene (V1aR, encoding a vasopressin receptor) in the ventral forebrain changed the behaviour of a normally promiscuous species into a pair-forming animal (Lim et al., 2004).”
Implications of breaking mother–young social bonds (2008, background): “For example, in voles, variations in ER-a and vasopressin receptor densities in specific brain regions, mediated by estrogens and androgens and by allelic differences in the length of polymorphic microsatellites in the 50 region of the vasopressin receptor gene, determine the extent to which males f”
The vertebrate social behavior network: evolutionary themes and variations. (2005, neutral): “…and the features of these systems are associated with seasonal variation, sex differences, and species divergence in behavior (reviews: De Vries and Boyle, 1998; Foran and Bass, 1999; Insel and Young, 2000; Goodson and Bass, 2001; Panzica et al., 2001; Keverne and Curley, 2004; Lim et al., 2004a).”
A developmental, mentalization-based approach to the understanding and treatment of borderline personality disorder (2009, background): “pecially in males (Caldwell, Lee, Macbeth, & Young, 2008; Lim et al., 2004).”