Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial.

By P. Guillou, P. Quirke, H. Thorpe, Joanne Walker, D. Jayne, Adrian Smith, R. Heath, Julia M. Brown. The Lancet, 2005

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A randomized trial of laparoscopic versus open surgery for rectal cancer. (2015, neutral): “(%) I: healthy 156 (22) 65 (19) II: mild systemic disease 386 (55) 211 (61) III: severe systemic disease 131 (19) 61 (18) IV: severe life-threatening systemic disease 5 (1) 1 (<1)”
Laparoscopy in Combination with Fast Track Multimodal Management is the Best Perioperative Strategy in Patients Undergoing Colonic Surgery: A Randomized Clinical Trial (LAFA-study) (2011, background): “All patients were discharged if they complied with the following predefined discharge criteria: (1) adequate pain control with paracetamol and/or nonsteroidal antiinflammatory drugs (2) ability to tolerate solid food (3) absence of nausea (4) passage of first flatus and/or first stool (5) mobilizati”
Extended Clavien-Dindo classification of surgical complications: Japan Clinical Oncology Group postoperative complications criteria (2015, methodology): “Few randomized controlled trials (RCTs) [3] have used this classification system, with individual parochial definitions of surgical complications being used in most surgical RCTs [4–6].”