Synthetic Messenger RNA as a Tool for Gene Therapy

By Pter M. Rabinovich, M. Komarovskaya, Zhi-jia Ye, C. Imai, Dario Campana, E. Bahceci, S. Weissman. 2006

73 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Oncology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Alexander Meissner
2. James J. Collins
3. Zachary D. Smith
4. Derrick J. Rossi
5. Dongbin Xiu

In Molecular Biology

1. Yuin Han Loh
2. Alexander Meissner
3. G. Daley
4. James J. Collins
5. Zachary D. Smith
6. Derrick J. Rossi
7. S. Yamanaka
8. Dongbin Xiu

In Oncology

1. James J. Collins

Citations in the corpus

• Chimeric Receptor mRNA Transfection as a Tool to Generate Antineoplastic Lymphocytes (2008, unknown): “As the efficiencies of Amaxa electroporation programs were similar for both DNA and RNA (Amaxa, 2006; Rabinovich et al. , 2006), we first determined CTL transfectability under various conditions by using a pmaxGFP plasmid DNA.”
• mRNA-based therapeutics — developing a new class of drugs (2014, unknown): “ARCA-capped mRNAs exhibited superior translational efficiency in various cell types 37,38 .”
• Highly efficient reprogramming to pluripotency and directed differentiation of human cells using synthetic modified mRNA (2010, background): “Indeed, the use of RNA transfection to express cancer or pathogen antigens for immunotherapy is already an active research area (Rabinovich et al., 2006, 2008; Van den Bosch et al., 2006; Weissman et al., 2000), and such approaches may benefit from the nonimmunogenic properties of modified RNAs.”