Increased insect resistance in transgenic wheat stably expressing trypsin inhibitor CMe

By F. Altpeter, I. Díaz, H. McAuslane, K. Gaddour, P. Carbonero, I. Vasil. Molecular breeding, 2004

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Genetic enrichment of cereal crops via alien gene transfer: New challenges (2001, background): “…nubilalis) Armstrong et al., 1995 WHEAT (Triticum aestivum L.) Bob White trypsin inhibitor (cme enhanced resistance to Angoumois Grain Altpeter et al., 1999 BTI-Cme) Moth (Sitotroga cerealella) Bob White agglutinin (gna) decreased fecundity of aphids Stoger et al., 1999 (Sitobion…”
Pathogenesis-related proteins and their genes in cereals (2001, background): “Altpeter et al. (1999) introduced the gene encoding a barley trypsin inhibitor, cme, into immature wheat embyros.”
Genetic Transformation of Crops for Insect Resistance: Potential and Limitations (2004, background): “A significant reduction in survival rate of the Angoumois grain moth (Sitotroga cerealella) has been observed on transgenic wheat seeds expressing the trypsin inhibitor from barley (Altpeter et al., 1999).”
Characteristics of Plant Proteinase Inhibitors and Their Applications in Combating Phytophagous Insects (2005, unknown): “The failure resulted from either the ineffectiveness of some PIs on particular insects (Altpeter et al., 1999) or the adaptation of insects to them (Cloutier et al.”
Plant protease inhibitors: a defense strategy in plants (2007, background): “However, only early-instar larvae were inhibited in transgenic seeds, and expression of BTI protein in transgenic leaves did not have a significant protective effect against leaf-feeding insects (Altpeter et al., 1999).”