Draft genome of the wheat A-genome progenitor Triticum urartu

By H. Ling, Shancen Zhao, Dongcheng Liu, Junyi Wang, Hua Sun, Chi Zhang, Huajie Fan, Dong Li, Lingli Dong, Y. Tao and 43 more. Nature, 2013

693 citations recorded by the source corpus.

Bread wheat (Triticum aestivum, AABBDD) is one of the most widely cultivated and consumed food crops in the world. However, the complex polyploid nature of its genome makes genetic and functional analyses extremely challenging. The A genome, as a basic genome of bread wheat and other polyploid wheats, for example, T. turgidum (AABB), T. timopheevii (AAGG) and T. zhukovskyi (AAGGAmAm), is central to wheat evolution, domestication and genetic improvement. The progenitor species of the A genome is the diploid wild einkorn wheat T. urartu, which resembles cultivated wheat more extensively than do Aegilops speltoides (the ancestor of the B genome) and Ae. tauschii (the donor of the D genome), especially in the morphology and development of spike and seed. Here we present the generation, assembly and analysis of a whole-genome shotgun draft sequence of the T. urartu genome. We identified protein-coding gene models, performed genome structure analyses and assessed its utility for analysing agronomically important genes and for developing molecular markers. Our T. urartu genome assembly provides a diploid reference for analysis of polyploid wheat genomes and is a valuable resource for the genetic improvement of wheat.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/8301adf5e928030be09f447ed62a238073c63450

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Plant Science

1. Caixia Gao
2. Kunling Chen
3. Xianchun Xia
4. Yanpeng Wang
5. Zhonghu He
6. Bin Han
7. Tariq Mahmood
8. Xuehui Huang

Citations in the corpus

• Wheat seed storage proteins: Advances in molecular genetics, diversity and breeding applications (2014, background): “Now, the available whole genome shotgun draft 459 sequences of T. urartu (Ling et al. 2013) and Ae. tauschii (Jia et al. 2013) will accelerate 460 deeper and more systematic studies to meet future challenges in understanding wheat 461 processing qualities.”
• Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA (2016, positive): “First, we developed the TECCDNA-based genome-editing method by working with the three homoeologues of TaGASR7 ( TaGASR7-A1, -B1 and -D1 ), which have been implicated in the control of grain length and weight 7 .”
• Natural variations and genome-wide association studies in crop plants. (2014, methodology): “Generating a high-quality assembly for the large, complex crop genomes of species such as bread wheat (Triticum aestivum) remains a significant challenge (10, 51, 65).”
• Piercing the dark matter: bioinformatics of long-range sequencing and mapping (2018, background): “In some cases, the assembled sequences have been substantially shorter than the average gene size, rendering the assembled sequence much less useful than earlier reference genomes 27,28 .”
• Ancient hybridizations among the ancestral genomes of bread wheat (2014, background): “tauschii) (7, 17, 18) to generate a genome-wide sample of 275 gene trees and to estimate the phylogenetic history of the A, B, and D genome lineages.”