Predictive value of grade for metastasis development in the main histologic types of adult soft tissue sarcomas

By J. Coindre, P. Terrier, L. Guillou, V. Le Doussal, François Collin, D. Ranchère, X. Sastre, M. Vilain, F. Bonichon, B. N'Guyen Bui. Cancer, 2001

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MDM2 and CDK4 Immunostainings Are Useful Adjuncts in Diagnosing Well-Differentiated and Dedifferentiated Liposarcoma Subtypes: A Comparative Analysis of 559 Soft Tissue Neoplasms With Genetic Data (2005, background): “Specificity for MDM2 and CDK4 staining was calculated as the ratio of unstained nonALT-WDLPS/DDLPS tumors to the total number of nonALT-WDLPS/DDLPS.”
Soft Tissue Sarcomas (2001, background): “Currently, more than 50 histologic types of soft tissue sarcoma have been identified (Table 1), but the most common are malignant fibrous histiocytoma (28%), leiomyosarcoma (12%), liposarcoma (15%), synovial sarcoma (10%), and malignant peripheral nerve sheath tumors (6%).(3) Rhabdomyosarcoma is the”
Pathology of Peripheral Nerve Sheath Tumors: Diagnostic Overview and Update on Selected Diagnostic Problems (2012, neutral): “One caveat is that this system has not been demonstrated to be of prognostic value in MPNST [22], highlighting the need for large multi-institutional studies sufficiently powered to answer the specific question of grading and prognostic relevance, in particular separating a high-grade category into ”