The effect of pain on cognitive function: a review of clinical and preclinical research.
By O. Moriarty, B. McGuire, David P. Finn. Progress in neurobiology, 2011
1,039 citations recorded by the source corpus.
Cognitive impairment is commonly associated with the pain experience. This impairment represents a major obstacle to daily activities and rehabilitation, especially in the chronic pain population. Here we review clinical and preclinical studies that have investigated pain-related alterations in cognition. These include impaired attentional, executive and general cognitive functioning. We describe the anatomical, neurochemical and molecular substrates common to both cognitive processing and supraspinal pain processing, and present the evidence for their involvement in pain-related cognitive impairment. We also examine the added complexity of cognitive impairment caused by analgesic medications and how this can further impact on morbidity in chronic pain patients. The need for a better understanding of the mechanisms of both pain-induced and treatment-related cognitive impairment is highlighted. Further research in this area will aid our understanding of patient symptoms and their underlying pathophysiology, ultimately leading to increased provision of guided therapy.
Subfields: Cognitive Neuroscience, Pharmacology, Physiology
View Paper: https://www.semanticscholar.org/paper/8254dfd524d19bd43732270c9b8b8f8daa033835
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In Cognitive Neuroscience
Citations in the corpus
- Psychological Considerations in the Assessment and Treatment of Pain in Neurorehabilitation and Psychological Factors Predictive of Therapeutic Response: Evidence and Recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation (2016, background): “…delayed recall, reaction times, prospective memory, psychomotor skills, recognition of mental and emotional states, and executive functions (Hart et al., 2000; Jongsma et al., 2011; Moriarty et al., 2011; Beaupré et al., 2012; Shin et al., 2013; Miller and Radford, 2014; Zhang et al., 2014).”