Efficacy of a pneumococcal conjugate vaccine against acute otitis media.
By J. Eskola, T. Kilpi, A. Palmu, J. Jokinen, Mervi Eerola, J. Haapakoski, E. Herva, A. Takala, H. Käyhty, P. Karma and 4 more. New England Journal of Medicine, 2001
1,479 citations recorded by the source corpus.
Subfields: Epidemiology, Microbiology, Otorhinolaryngology
View Paper: https://www.semanticscholar.org/paper/817fa9bd3983292eb30ce5619b259fe31a5fbfa3
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Citations in the corpus
- Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004. (2007, background): “Increases in rates of nasopharyngeal carriage and otitis media caused by nonvaccine serotypes have been demonstrated in persons who received pneumococcal conjugate vaccine [5, 9-13].”
- Invasive pneumococcal disease caused by nonvaccine serotypes among alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage. (2007, background): “In a pneumococcal conjugate vaccine trial in Finland, serotype replacement following vaccination resulted in an increase in acute otitis media caused by nonvaccine serotypes.(35) In 2004, Ghaffar et al(36) hypothesized that the reduction of PCV7 type colonization and replacement by nonPCV7 colonizat”
- Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potential. (2003, background): “, the capsule is likely to be of far less importance for acute otitis media, because unencapsulated pneumococcal isolates can cause this disease, whereas unencapsulated strains very rarely cause invasive disease [1, 24, 30]), differences in the response of the host immune system to bacterial challen”
- Effectiveness of heptavalent pneumococcal conjugate vaccine in children younger than five years of age for prevention of pneumonia (2002, background): “Serotype replacement was observed in the Finnish otitis media study.(26) These investigators reported a 33% increase in otitis media caused by nonvaccine or cross-reacting serotypes in recipients of PCV.”