A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity
By T. Frayling, Nicholas J. Timpson, M. Weedon, Eleftheria Zeggini, R. Freathy, C. Lindgren, J. Perry, K. Elliott, H. Lango, N. W. Rayner and 31 more. Science, 2007
4,583 citations recorded by the source corpus.
Subfields: Genetics, Pediatrics, Perinatology and Child Health
View Paper: https://www.semanticscholar.org/paper/810f09256aba90219f7be6f7e5b6771a3303c6cf
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
- Gibran Hemani
- George Davey Smith
- Jian Yang
- Peter M. Visscher
- Gonçalo R. Abecasis
- Wei-Min Chen
- Serena Sanna
- David Schlessinger
In Pediatrics, Perinatology and Child Health
- Gibran Hemani
- George Davey Smith
- Ruth J. F. Loos
- Stephen Burgess
- J. Bowden
- S. Thompson
- Deborah Lawlor
- Dylan S. Small
Citations in the corpus
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency (2015, neutral): “The two mA demethylases (FTO and AlkBH5) have been associated with human body weight (Dina et al., 2007; Frayling et al., 2007; Do et al., 2008) and mouse fertility (Zheng et al.”
- Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits (2007, result): “In addition, two other large independent studies also show association of SNPs in FTO with increased BMI [49,50].”
- Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry (2018, background): “Furthermore, the common SNP associated with the largest known effect on BMI, that in the FTO gene (16), was not associated with WHRadjBMI (rs1421085, P = 0.”