Aqueous-phase chemistry and bactericidal effects from an air discharge plasma in contact with water: evidence for the formation of peroxynitrite through a pseudo-second-order post-discharge reaction…

By Petr Lukes, E. Doležalová, I. Sisrova, M. Člupek. 2014

1,091 citations recorded by the source corpus.

The formation of transient species (OH·, NO2·, NO radicals) and long-lived chemical products (O3, H2O2, , ) produced by a gas discharge plasma at the gas–liquid interface and directly in the liquid was measured in dependence on the gas atmosphere (20% oxygen mixtures with nitrogen or with argon) and pH of plasma-treated water (controlled by buffers at pH 3.3, 6.9 or 10.1). The aqueous-phase chemistry and specific contributions of these species to the chemical and biocidal effects of air discharge plasma in water were evaluated using phenol as a chemical probe and bacteria Escherichia coli. The nitrated and nitrosylated products of phenol (4-nitrophenol, 2-nitrophenol, 4-nitrocatechol, 4-nitrosophenol) in addition to the hydroxylated products (catechol, hydroquinone, 1,4-benzoquinone, hydroxy-1,4-benzoquinone) evidenced formation of NO2·, NO· and OH· radicals and NO+ ions directly by the air plasma at the gas–liquid interface and through post-discharge processes in plasma-activated water (PAW) mediated by peroxynitrite (ONOOH). Kinetic study of post-discharge evolution of H2O2 and in PAW has demonstrated excellent fit with the pseudo-second-order reaction between H2O2 and . The third-order rate constant k = 1.1 × 103 M−2 s−1 for the reaction was determined in PAW at pH 3.3 with the rate of ONOOH formation in the range 10−8–10−9 M s−1. Peroxynitrite chemistry was shown to significantly participate in the antibacterial properties of PAW. Ozone presence in PAW was proved indirectly by pH-dependent degradation of phenol and detection of cis,cis-muconic acid, but contribution of ozone to the inactivation of bacteria by the air plasma was negligible.

Subfields: Biophysics, Health, Toxicology and Mutagenesis, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/810b0d3f7776cbf71f0879e1eb91c4430792d484

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Citations in the corpus

Physicochemical properties of bactericidal plasma-treated water (2016, background): “Certain studies even demonstrated that the bactericidal activity of plasmairradiated water could be reproduced by mixing H2O2 and nitrite (NO2 ) under acidic conditions [30, 31].”
Measurement of reactive species generated by dielectric barrier discharge in direct contact with water in different atmospheres (2017, background): “Transient species such as peroxynitrous acid and peroxynitrite are involved as intermediates in conversion of nitrite into nitrate in the liquid, and significantly participate in plasmainduced aqueous chemistry and antimicrobial properties of plasma-activated water [31, 99].”
Plasma–liquid interactions: a review and roadmap (2016, background): “This bias can be avoided by adding azide to the sample of H2O2 prior to mixing with the acidic analytic reagent [486].”