Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.

By Thomas B Knudsen, K. Houck, Nisha S. Sipes, Amar V. Singh, Richard S. Judson, Matt T. Martin, A. Weissman, N. Kleinstreuer, H. Mortensen, David M. Reif and 5 more. 2011

139 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Pharmacology, Small Animals

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. R. Kavlock
2. Richard S. Judson
3. Kamel Mansouri
4. Douglas B. Kell
5. David Broadhurst

In Small Animals

1. Richard S. Judson
2. R. Kavlock
3. Ann M. Richard

Citations in the corpus

• Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor. (2015, methodology): “These include 3 cell-free biochemical radioligand ER binding assays [Novascreen/NVS: (Knudsen et al. , 2011; Sipes et al. , 2013)]; a set of 3 protein complementation assays that measure formation of ER homodimers or hetero-dimers and test for activity against both ER-alpha and ER-beta, (each…”
• Improving the Human Hazard Characterization of Chemicals: A Tox21 Update (2013, background): “…550 in vitro and lower organism in vivo assays by various contract and government laboratories (Chandler et al. 2011; Dix et al. 2007; Houck et al. 2009; Judson et al. 2010; Knight et al. 2009; Knudsen et al. 2011; Martin et al. 2009a, 2009b, 2010, 2011; Padilla et al. 2012; Rotroff et al. 2010).”