Vascular smooth muscle cells in atherosclerosis

By Gemma Basatemur, H. Jørgensen, Murray C H Clarke, M. Bennett, Z. Mallat. Nature Reviews Cardiology, 2019

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NF-κB in biology and targeted therapy: new insights and translational implications (2024, background): “398 The major pathogenic mechanism underlying the formation of atherosclerotic plaques was believed to be the phenotypic switching of VSMCs from contractile to proliferative synthetic types in response to arterial in ﬂ ammation.”
Atherosclerosis: Recent developments (2022, methodology): “Bone-related proteins, such as BMP-1, BMP-4, and matrix GLA protein, are often expressed in such regions (Basatemur et al., 2019; Mori et al., 2018).”
Inflammation and atherosclerosis: signaling pathways and therapeutic intervention (2022, background): “Although the prevailing point is that VSMCs exert beneficial roles in advanced atherosclerosis as they can stabilize fibrous cap and are major cells producing ECM, single-cell RNA-sequencing combination with lineage tracing have revealed much morediverse phenotypes of VSMCs in the various stages of ”