Trace amines: Identification of a family of mammalian G protein-coupled receptors

By B. Borowsky, N. Adham, K. A. Jones, R. Raddatz, R. Artymyshyn, K. Ogozalek, M. Durkin, P. Lakhlani, J. A. Bonini, S. Pathirana and 7 more. Proceedings of the National Academy of Sciences of the United States of America, 2001

892 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/7ffc5235bf6c9fef792dd0f7da51b133f05e221e

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Citations in the corpus

Thyroid hormone regulation of metabolism. (2014, background): “The thyronamines bind to G protein-coupled trace amino acid associated receptor 1 (TAAR1) and adrenergic receptor 2 (24, 197).”
The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity (2008, background): “These receptors were first identified as brain receptors for the trace amines, a collection of amines that are present at low concentrations in the central nervous syste”
Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands (2002, background): “These comprise 15 new receptors distinct from the classical biogenic amine receptors that apparently bind the trace amines tyramine, -phenylethylamine, tryptamine and octopamine [ 56 ].”
Review of octopamine in insect nervous systems (2012, neutral): “OCT is a sympathomimetic amine and known as a false neurotransmitter because it can be stored in vesicles replacing endogenous classical amines such as norepinephrine, dopamine, and serotonin.(7) OCT is coreleased with other catecholamines, so many of its effects may be indirect, and the existence o”
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003, background): “Unlike the normal monoamine receptors, this receptor is located within the cell cytosol, possibly on vesicular membranes (Borowsky et al., 2001).”
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine (2014, positive): “C to serotonin (Borowsky et al., 2001; Zucchi et al., 2006), aswell as a ligand for the sigma-2 receptor (Fontanilla et al.”
Mechanisms of neurotransmitter release by amphetamines: a review. (2005, background): “There has been a resurgence in interest in this topic due to the discovery of a family of 15 mammalian G protein-coupled trace amine receptors (Borowsky et al., 2001; Bunzow et al., 2001).”