Memory consolidation, retrograde amnesia and the hippocampal complex.

By Lynn Nadel, Morris Moscovitch. 1997

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Citations in the corpus

Structural Synaptic Plasticity Has High Memory Capacity and Can Explain Graded Amnesia, Catastrophic Forgetting, and the Spacing Effect (2014, background): “Although there are not yet final experimental answers [34,105], both predictions may be in conflict with evidence that novel memories are buffered and replayed by the hippocampus for a limited time only [34,38,39] and that, depending on the lesion size, graded amnesia can reach back to early childho”
Memory Efficient Experience Replay for Streaming Learning (2018, background): “two networks [26], [40]: one that learns fast inspired by the hippocampus and one that learns slowly inspired by the neocortex [59].”
Replay in Deep Learning: Current Approaches and Missing Biological Elements (2021, neutral): “Bilateral removal of the hippocampus results in anterograde amnesia and the inability to form new semantic memories (Nadel & Moscovitch, 1997).”
Reactivation of Hippocampal Cell Assemblies: Effects of Behavioral State, Experience, and EEG Dynamics (1999, background): “…role in the initial encoding of a memory but that, with time, the memory becomes independent of the hippocampus (Scoville and Milner, 1957; McGaugh and Herz, 1972; MacKinnon and Squire, 1989; Kim and Fanselow, 1992; for review, see Zola-Morgan and Squire, 1993; but see Nadel and Moscovitch, 1997).”
The restless engram: consolidations never end. (2012, background): “There is also a growing realization that the classic temporal gradient of retrograde amnesia, challenged in the development of the multiple-trace theory of Nadel and Moscovitch (1997), may not be reliably secured in animal models.”
Theta rhythm of navigation: Link between path integration and landmark navigation, episodic and semantic memory (2005, background): “A prediction of the presented framework is that episodic memory relies on the intact entorhinal–hippocampal system (Nadel and Moscovitch, 1997; Nadel et al., 2000; Tulving, 2002) generating theta oscillations.”
Memory for events and their spatial context: models and experiments. (2001, background): “One recent development of the model proposes that, over time, events can be rehearsed, creating new event-codes on each rehearsal ( Nadel & Moscovitch 1997 ).”
The molecular and systems biology of memory. (2014, unknown): “Driven by these observations and corresponding findings in animal models, Nadel and Moscovitch (1997) proposed the ‘‘multiple trace theory,’’ which posits that the hippocampus rapidly and obligatorily encodes all episodic information.”
Tracelink: A model of consolidation and amnesia (2005, methodology): “Neither multiple trace theory (Nadel & Moscovitch, 1997; Nadel, Samsonovitch, Ryan, & Moscovitch, 2000) nor what one could call the semantisation hypothesis (Cermak, 1984; Meeter & Murre, in press; Rosenbaum, Winocur, & Moscovitch, 2001) has been worked out in much detail.”
Selectionist and Evolutionary Approaches to Brain Function: A Critical Appraisal (2012, background): “we are concerned with how intrinsic connections (within a cortical region) are entrained by extrinsic inputs from the hippocampus (Nadel and Moscovitch, 1997; Nadel et al., 2000, 2007).”
The Role of Sleep in Cognition and Emotion (2009, methodology): “This has led to the emergence of alternate consolidation models, most notably Nadel and Moscovitch’s “multiple trace theory” (Nadel & Moscovitch 1997; Moscovitch & Nadel 1998), which posits that hippocampal involvement is always critical for the retrieval of episodic (but not semantic) memories,…”
Hippocampus and contextual fear conditioning: Recent controversies and advances (2001, methodology): “…temporally graded, i.e., memories acquired just prior to the lesion (recent memory) are more severely impacted than those acquired several years before (remote memory; Scoville and Milner, 1957; Squire and Alvarez, 1995; Knowlton and Fanselow, 1998; but see also Nadel and Moscovitch, 1997, 1998).”
ReviewMemory Consolidation in Sleep: Dream or Reality (2004, background): “As a group, the TCAs have no adverse actions on Nadel and Moscovitch (1997) described memory consolmemory (Thompson and Trimble, 1982; Deptula and Po- idation as the “neural processing that occurs after informara, 1990; Thompson, 1991; Amado-Boccara et al., mation is initially registered which…”
Dissociating the past from the present in the activity of place cells (2006, background): “…and Milner, 1957; Squire et al., 2004) and, without entering the controversy of whether this role is temporary or not (Squire et al., 2001; Nadel and Moscovitch, 1997), there is ample evidence for its involvement in the recollection of events of one’s life (Vargha-Khadem et al., 1997;…”
Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory (2005, background): “…for autobiographical episodes, and perhaps even for public events and personalities, always depend on the hippocampus (Sanders & Warrington, 1971; Nadel & Moscovitch, 1997; Fujii et al. 2000; Maguire, 2001a; Ryan et al. 2001; Corkin, 2002; Maguire & Frith, 2003; Piolino et al. 2003; Addis et al.…”