Inflammation in osteoarthritis.

By S. Abramson. Journal of Rheumatology Supplement, 2004

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The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis (2014, background): “According to the latest medical knowledge, the participation of the immune system in the development and progression of OA is one of the key elements in the pathogenesis of the disease [3].”
The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis. (2020, background): “Moreover, excessive ROS induces a senescent phenotype in cells (Goldring and Otero, 2011; Wiley and Campisi, 2016).”
The Long-term Consequence of Anterior Cruciate Ligament and Meniscus Injuries (2007, background): “Osteoarthritis has been regarded as a noninflammatory arthritis, but improved detection methods show that inflammatory pathways are up-regulated.(1) Several of the environmental risk factors mentioned (obesity, joint injury, work- or leisure-related joint overload) are mechanical, and recent studies”