Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry.

By G. Lichtenstein, B. Feagan, R. Cohen, B. Salzberg, R. Diamond, D. Chen, M. Pritchard, W. Sandborn. Clinical Gastroenterology and Hepatology, 2006

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Guidelines for the management of inflammatory bowel disease in adults (2011, background): “Effects due to supra-physiological doses include cosmetic (acne, moon face, oedema), sleep and mood disturbance, dyspepsia or glucose intolerance. The uncontrolled observational data from the large TREAT registry suggests a twofold RR of infection associated with steroid usage versus no steroid usag”
Ulcerative Colitis Practice Guidelines in Adults: American College of Gastroenterology, Practice Parameters Committee (2010, background): “Additional information regarding risk of infection is available from the Therapy, Resource, Evaluation, and Assessment Tool registry, an ongoing observational infliximab safety registry in patients with CD, which contains approximately 6,000 patients with 16,000 years of patient follow-up, half of w”