Global epidemiology of hepatocellular carcinoma: an emphasis on demographic and regional variability

By K. McGlynn, Jessica L. Petrick, W. London. Clinical Liver Disease, 2015

808 citations recorded by the source corpus.

Liver cancer is the second leading cause of global cancer mortality. The major risk factors for hepatocellular carcinoma (HCC) are being addressed with success by prevention efforts. Vaccination against hepatitis B virus has reduced incidence of HCC in Taiwan and is partly responsible for lower rates in China. New infections with hepatitis C virus are low in developed countries because of prevention of posttransfusion infections and reduced exposure to HCV by drug users. Aflatoxin exposure has been reduced by better grain storage and dietary changes. Obesity, metabolic syndrome, and diabetes are increasing in developed and developing countries and will lead to more cases of HCC.

Subfields: Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/7e2556cad69939fbefd82fc2f18109188088aa3a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. R. Siegel
2. A. Jemal
3. Elizabeth E. Ward

In Hepatology

1. A. Jemal
2. Elizabeth E. Ward

Citations in the corpus

• Global Cancer Incidence and Mortality Rates and Trends—An Update (2015, background): “In Japan, reduced chronic schistosomiasis infection andHCV infection through improved blood donation practices and policies that deterred intravenous drug abuse are thought to have contributed to declining liver cancer rates (68, 70).”