Why have clinical trials in sepsis failed?

By J. Marshall. Trends in Molecular Medicine, 2014

733 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Endocrinology, Diabetes and Metabolism, Epidemiology

View Paper: https://www.semanticscholar.org/paper/61118aac9757165630e4be87c09a240acc03559d

Citations in the corpus

• Dengue and severe dengue (2025, unknown): “Indeed, important lessons can be drawn from previous failed sepsis trials, and more recently from COVID-19 trials, that highlight the need to identify and target appropriate patient sub-populations to demonstrate clinical benefit while minimizing potential harm from immune modulation (323, 324).”