A role for mitochondria in NLRP3 inflammasome activation

By Rongbin Zhou, Amir S. Yazdi, P. Menu, J. Tschopp. Nature, 2011

273 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Mitochondrial dysfunction: mechanisms and advances in therapy (2024, background): “156 Upon activation by NLRP3 activators, TLR leads to the production of oxidized mtDNA fragments through the IRF1-dependent transcription of CMPK2, a key enzyme in mtDNA synthesis.”