Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.

By Bruno E. Correia, Y. Ban, M. Holmes, Hengyu Xu, Katharine Ellingson, Z. Kraft, Chris Carrico, E. Boni, D. Sather, C. Zenobia and 8 more. 2010

223 citations recorded by the source corpus.

Subfields: Molecular Biology, Radiology, Nuclear Medicine and Imaging, Virology

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In Molecular Biology

1. Bruno E. Correia
2. Che Yang
3. S. Rosset
4. J. Bonet
5. A. Scheck
6. Freyr Sverrisson

Citations in the corpus

• Rosetta FunFolDes – A general framework for the computational design of functional proteins (2018, methodology): “…(Chevalier et al., 2017); however, these efforts were limited to linear motifs that carried the functions, and the functionalization was mainly accomplished by side-chain grafting (Correia et al., 2010; Kulkarni et al., 2015) and relied on screening of a much larger number of designed proteins.”