Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An Update

By Ekarat Jantratid, Niels Janssen, C. Reppas, J. Dressman. Pharmaceutical Research, 2008

760 citations recorded by the source corpus.

Subfields: Gastroenterology, Pharmaceutical Science, Surgery

View Paper: https://www.semanticscholar.org/paper/7d72da660320600b0e01ed6707b2ecd325757305

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Pharmaceutical Science

1. J. Dressman

In Surgery

1. M. Bergstrand

Citations in the corpus

• Simulated Biological Fluids with Possible Application in Dissolution Testing (2011, methodology): “It has been suggested that the most suitable medium representing the fed-state stomach is the homogenized form of the meal used in clinical studies, but difficulties in the analysis of the drug released into the medium put some limitations on its use (13).”
• PBPK models for the prediction of in vivo performance of oral dosage forms. (2014, methodology): “This section will focus on the best methods to estimate in vivo solubility used in Computational Oral Absorption Simulation (COAS) (Sugano, 2009b).”