Tonotopic organization of human auditory cortex

By Colin J. Humphries, E. Liebenthal, Jeffrey R. Binder. 2010

378 citations recorded by the source corpus.

The organization of tonotopic fields in human auditory cortex was investigated using functional magnetic resonance imaging. Subjects were presented with stochastically alternating multi-tone sequences in six different frequency bands, centered at 200, 400, 800, 1600, 3200, and 6400 Hz. Two mirror-symmetric frequency gradients were found extending along an anterior-posterior axis from a zone on the lateral aspect of Heschl's gyrus (HG), which responds preferentially to lower frequencies, toward zones posterior and anterior to HG that are sensitive to higher frequencies. The orientation of these two principal gradients is thus roughly perpendicular to HG, rather than parallel as previously assumed. A third, smaller gradient was observed in the lateral posterior aspect of the superior temporal gyrus. The results suggest close homologies between the tonotopic organization of human and nonhuman primate auditory cortex.

Subfields: Artificial Intelligence, Cognitive Neuroscience

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In Artificial Intelligence

1. Peter Alexander Jansen
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3. Scott Watter
4. Andrew Zalesky
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In Cognitive Neuroscience

1. Michael Breakspear
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Citations in the corpus

• Criticality in the brain: A synthesis of neurobiology, models and cognition. (2017, background): “Each bundle is tuned to a particular natural frequency and adjacent cells respond maximally to successive pitches, giving rise to a tonotopic map in the cochlea (Romani et al., 1982).”
• Functional Correlates of the Antero-Lateral Processing Hierarchy in Human Auditory Cortex (2011, background): “Several previous studies have attempted to map auditory fields via tonotopic or cochleotopic organization (Formisano et al., 2003; Talavage et al., 2004; Humphries et al., 2010).”
• A Task-Optimized Neural Network Replicates Human Auditory Behavior, Predicts Brain Responses, and Reveals a Cortical Processing Hierarchy. (2018, neutral): “There is growing consensus that frequency and modulation tuning explain aspects of primary auditory cortical responses (Depireux et al., 2001; Humphries et al., 2010; Miller et al., 2002; Santoro et al., 2014), but the organization of the rest of auditory cortex into regions and pathways remains unr”
• Strong systematicity through sensorimotor conceptual grounding: an unsupervised, developmental approach to connectionist sentence processing (2012, methodology): “The SOM was originally formulated by Kohonen (1982) as an unsupervised analogue to the topographic organisation found in perceptual cortex (e.g. Cansino,Williamson, and Karron 1994).”