A Modular Approach to the ECVAM Principles on Test Validity

By T. Hartung, S. Bremer, S. Casati, S. Coecke, R. Corvi, S. Fortaner, L. Gribaldo, M. Halder, S. Hoffmann, A. Roi and 5 more. Alternatives to laboratory animals : ATLA, 2004

362 citations recorded by the source corpus.

Subfields: Small Animals, Statistics and Probability

View Paper: https://www.semanticscholar.org/paper/7c62aeec20b23799fe0562057b032085967b12dd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. W. Lilienblum
2. J. Valk
3. D. Brunner
4. T. Gebel
5. G. Gstraunthaler
6. Anna Price
7. K. D. Smet
8. Lisbeth E. Knudsen

Citations in the corpus

• Optimization of chemically defined cell culture media--replacing fetal bovine serum in mammalian in vitro methods. (2010, methodology): “When serum is being replaced in an already validated in vitro method, the new method should be validated in a catch-up study (Hartung et al., 2004).”
• Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH) (2008, background): “Recently, a “modular approach“ has been proposed that is expected to accelerate the validation process (Hartung et al. 2004).”