Faculty Opinions recommendation of Piezo proteins are pore-forming subunits of mechanically activated channels.
By C. Stucky, Andy D. Weyer, Marie E. Barabas. 2012
389 citations recorded by the source corpus.
Subfields: Biomedical Engineering, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/7c467af7e593befc638e2cca8fc198c347be1811
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In Molecular Biology
In Physiology
Citations in the corpus
- Chemical activation of the mechanotransduction channel Piezo1 (2015, methodology): “DOI: 10.7554/eLife.07369 1 of 11 channel-forming proteins, as opposed to accessory subunits (Coste et al., 2012).”
- Reverse genetic screening reveals poor correlation between Morpholino-induced and mutant phenotypes in zebrafish (2014, background): “In zebrafish, fam38a encodes the homolog of Piezo1, a multipass transmembrane protein that functions as a mechanosensory channel (Coste et al., 2012; Kim et al., 2012b).”
- Piezo1, a mechanically activated ion channel, is required for vascular development in mice (2014, background): “2 mDa, with each monomer containing over 35 transmembrane domains (19).”