Alzheimer's disease.

By H. Querfurth, F. LaFerla. New England Journal of Medicine, 2010

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Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases (2019, background): “Studies have shown that these protein aggregates are strongly associated with neuroinflammation, synaptic loss and impaired neuronal function which ultimately lead to cognitive decline (135, 140, 141).”