Superoxide dismutases in the lung and human lung diseases.

By V. Kinnula, J. Crapo. American Journal of Respiratory and Critical Care Medicine, 2003

617 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology (2006, background): “There is direct evidence that the SOD enzymes have an important role in the molecular pathology of fibrosi”
Oxidative Stress, the Paradigm of Ozone Toxicity in Plants and Animals (2007, background): “Additionally, these cells can secrete, in the RTLF, extracellular isoforms of those enzymes (Comhair and Erzurum 2002; Kinnula and Crapo 2003).”
Oxidative Stress and Antioxidant Defense (2012, background): “It has also been detected in the bronchial epithelium, alveolar epithelium, and alveolar macrophages.(66,67) Overall, CuZnSOD and Mn-SOD are generally thought to act as bulk scavengers of superoxide radicals.”
Oxidative stress, inflammation, and cancer: how are they linked? (2010, background): “tissues, are protected against these oxidants by a variety of antioxidant mechanisms [13].”
Reactive Oxygen Species in Inflammation and Tissue Injury (2014, positive): “However, when their relative distribution is compared, the activities of CuZnSOD and MnSOD are lower in the lung compared with the other organs such as the liver, kidney, heart, and brain; whereas the EC-SOD activity has been reported to be much higher in the lung (217).”