WOMBAT—A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)

By K. Meyer. Journal of Zhejiang University SCIENCE B, 2007

805 citations recorded by the source corpus.

WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from http://agbu.une.edu.au/:_kmeyer/wombat.html

Subfields: Genetics, Plant Science

View Paper: https://www.semanticscholar.org/paper/7a9fc0d56c24d41a87ca038f1b611dd9cda5702e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. C. Klingenberg
2. Olivier Gimenez
3. B. Doligez
4. P. Villemereuil
5. Theodore Garland Jr.
6. Anthony R. Ives

In Plant Science

1. C. Klingenberg
2. Olivier Gimenez
3. B. Doligez
4. P. Villemereuil
5. Dean C. Adams

Citations in the corpus

• Thermal ramping rate influences evolutionary potential and species differences for upper thermal limits in Drosophila (2010, neutral): “1.0, Meyer 2007).”
• Comparing parent–offspring regression with frequentist and Bayesian animal models to estimate heritability in wild populations: a simulation study for Gaussian and binary traits (2013, methodology): “…REML is implemented in a wide choice of packages, including the (non free) ASReml software (Gilmour et al. 2006), the (free) WOMBAT software (Meyer 2007) and the (free) R package pedigreemm (Vazquez et al. 2010), while MCMC is only implemented in the (free) R package MCMCglmm (Hadfield…”
• MorphoJ: an integrated software package for geometric morphometrics (2011, methodology): “…covariance matrices and similar statistics, for which there are specialized software packages such as VCE (Groeneveld et al. 2008) or Wombat (Meyer 2007) that are freely available and can handle high-dimensional data as they are produced in geometric morpho-metrics, but M ORPHO J can import…”