Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridization.

By Kala Jessie, Mun Yik Fong, S. Devi, S. K. Lam, K. T. Wong. Journal of Infectious Diseases, 2004

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Prospects for a dengue virus vaccine (2007, background): “Although DENV varies greatly in its ability to produce viraemia in patients of all ages, high-titre viraemia (∼10 5 –10 6 infectious units per ml) occurs during the febrile period, seeding other areas such as the live”
Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms (2011, background): “All four dengue virus serotypes cause the same clinical manifestations and show similar patterns of systemic dissemination, with tropism principally for monocytes, macrophages and dendritic cell”
Dengue Virus Pathogenesis: an Integrated View (2009, background): “In contrast, there is evidence for the presence of DENV antigen in the pulmonary vascular endothelium (101).”
Dengue: a continuing global threat (2010, background): “There is also evidence of abundant replication of DENVs in liver parenchymal cells and in macrophages in lymph nodes, liver and spleen, as well as in peripheral blood monocytes 17 .”