Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease.

By B. Oberg, Elizabeth McMenamin, F. Lucas, E. McMonagle, J. Morrow, T. Ikizler, Jonathan Himmelfarb. Kidney International, 2004

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Oxidative stress and male infertility--a clinical perspective. (2008, background): “Chronic inflammation and oxidative stress are highly prevalent in patients with chronic kidney disease and end-stage renal disease (Oberg et al., 2004).”
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle? (2008, background): “Indeed, the elevation of plasma F2-isoprostane concentration, which represents a stable index of lipid peroxidation in vivo (in particular F2-isoprostane -III), has been demonstrated in CKD patients (110,111).”
Biomarkers of oxidative damage in human disease. (2006, background): “Plasma concentrations of protein carbonyls, as well as free F2-IsoPs and protein reduced thiols, differ significantly between chronic kidney disease patients and healthy persons; furthermore, such biomarkers of oxidative/nitrosative stress are significantly higher in patients with diabetes and hyper”