Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study.
By R. Bar-Or, R. Maya, L. Segel, Uri Alon, Arnold J. Levine, Moshe Oren. Proceedings of the National Academy of Sciences of the United States of America, 2000
624 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/7a1e358c6444bf75fb7ee4d8528f6c284c889207
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In Oncology
Citations in the corpus
- The p53 pathway: positive and negative feedback loops (2005, methodology): “This has been demonstrated first by measuring MDM-2 and p53 levels using Western blots of proteins from cells in culture undergoing a p53 stress response (Lev Bar-Or et al., 2000).”
- Encoding and Decoding Cellular Information through Signaling Dynamics (2013, neutral): “For example, p53 dynamics in response to DNA damage were originally described as damped oscillations when measured by western blot (Lev Bar-Or et al., 2000).”