Gut microbiota in the pathogenesis of inflammatory bowel disease

By A. Nishida, R. Inoue, Osamu Inatomi, S. Bamba, Y. Naito, A. Andoh. Clinical Journal of Gastroenterology, 2018

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How researchers see this paper

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Gut Microbiota and Immune System Interactions (2020, background): “protein 88 (MyD88) exhibit distinct intestinal microbiota and diminished production of antimicrobial peptides [74].”
A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease (2019, background): “The gut contains 1000-5000 different species, with 99% coming from Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria [30].”
Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review (2023, background): “Despite its importance, few is known about actors involved in human gut barrier function, since most of the data are limited to animal studies which have shown that microbiota changes can promote disruption of intestinal barrier homeostasis [37].”
Mechanisms of Disease: Inflammatory Bowel Diseases. (2019, background): “However, in order for microbiome changes to result in inappropriate and continuing inflammation, the integrity of the intestinal barrier separating the lumen and the mucosa should also be compromised (4, 5).”